VRTX Vertex Pharmaceuticals Incorporated

Stock NASDAQ Healthcare

US$513.04 -0.29% Latest close

Vertex Pharmaceuticals Incorporated (VRTX) trend channel, buy level and 3-month target on Trade The Path. Sector: Healthcare. Listed on NASDAQ. Levels below are fitted to this ticker's own swing highs and lows (Theil–Sen, log-price), then projected 3 months. If this ticker has no settled sample yet, treat the numbers as a geometric read, not a track record. Information only, not financial advice.

Mid-channel, rising on both timeframes

Price is between the two trend lines. Nothing to act on yet.

Read from the last 12 months of history we hold: rising, drifting +24% a year. The target of US$530.45 is below the nearest ceiling (US$549.98), so it does not depend on a breakout. What would overturn this: a close below US$494.81 β€” the floor of the channel being read β€” after which the trend, not the entry, is what was wrong.

12 months read from
US$495.16 – US$550.12 Rising channel, +24% a year
Position in that channel
33% 0% at the floor, 100% at the ceiling

Price history, with the path projected 3 months forward

US$300.0US$400.0US$500.0Oct 23Mar 24Aug 24Jan 25June 25Nov 25Apr 26Sept 26 today BuyTarget Our buy US$500.4 Β· est. 27 Oct 26Our target US$530.5 Β· est. 13 Nov 26
  • Daily close
  • Upper trend line (12 months)
  • Lower trend line (12 months)
  • Dashed after today: projected 3 months
  • Our buy
  • Our target

Suggested path

Buy at or below

US$500.43

level as at 27 Oct 2026

Our target

US$530.45

by 13 Nov 2026

Projected move

6.0%

gross, before costs

Price sits between our buy level and our target.

The lines are drawn where this stock has actually turned: 5 touches on the ceiling, 3 on the floor, each fitted to the slope that catches the most of them. Buying one average daily range below its 50-day mean, on heavier volume than usual and while it is still above its 200-day mean, has come up 791 times; measured against the 6% floor β€” the least a call has to be worth to be worth making, not what it aims at β€” 73% cleared it, typically in 34 days, with price going about 5% against the entry along the way (63% in the worst case we have on record). Trades that have not reached the target within 3 months are counted as misses, whatever they are worth at the time. The prices above are this stock’s own β€” its average, its volatility β€” but the setup is the same one we apply everywhere: derived on eight unrelated tickers, then confirmed on 87 others it was never fitted to. We deliberately do not tune it to each stock: doing so scores worse on history the tuning never saw β€” 58% against 71% β€” because it fits the past rather than the future. On this stock the setup has come up 10 times so far, reaching target 100% of the time. The sell price comes from where this stock is projected to be, not from a minimum worth taking: the fitted path reaches 13% above the entry within 90 days, and of the sizes that path supports, 6% is the one that has returned the most per day of money tied up here β€” measured over the 9 times this entry has come up on this chart, reached 100% of the time, typically in 17 days. Smaller sizes got there sooner but paid less for the weeks they used; larger ones need a break above the projected ceiling, which is not the base case. The date published is whichever is later: that typical time, or the day the projected path itself reaches the price. It is a prediction, so it can be revised: if the run tops out before it gets there, the target is cut to what is actually on the table and you are told the same day. An ordinary pullback is not treated as topping out β€” those go on to make a new high about 8 times in 10, so they are ridden through. What triggers the revision is price closing below its 50-day trend and staying there, after which the odds of recovery fall to roughly 3 in 10.

Upper line touches
5
Lower line touches
3
Fit confidence
65%
Fitted
16 Sept 2026

About Vertex Pharmaceuticals Incorporated

Vertex Pharmaceuticals Incorporated is a leading biotechnology firm primarily focused on the discovery, advancement, and marketing of innovative treatments, particularly for cystic fibrosis (CF). The company offers a range of approved medications for CF patients, including SYMDEKO/SYMKEVI, ORKAMBI, and KALYDECO, which target specific mutations within the cystic fibrosis transmembrane conductance regulator gene. Additionally, they provide TRIKAFTA for individuals with CF aged six years and older who possess at least one F508del mutation. Beyond its established CF therapies, Vertex maintains a robust and diverse clinical pipeline. This includes VX-864, currently in Phase 2 for alpha-1 antitrypsin (AAT) deficiency; VX-147, also in Phase 2, addressing APOL1-mediated focal segmental glomerulosclerosis (FSGS) and other serious kidney conditions; VX-880, a potential treatment for Type 1 Diabetes undergoing Phase 1/2 trials; VX-548, a NaV1.8 inhibitor in Phase 2 for various forms of acute, neuropathic, and musculoskeletal pain; and CTX001, which is in Phase 3 development for severe sickle cell disease (SCD) and transfusion-dependent beta-thalassemia (TDT). The company distributes its pharmaceutical products through specialty pharmacies and distributors across the United States, while international sales are facilitated via a network of specialty distributors, retail chains, hospitals, and clinics. Vertex also engages in numerous strategic collaborations with partners such as Affinia Therapeutics, Arbor Biotechnologies, CRISPR Therapeutics, Kymera Therapeutics, Mammoth Biosciences, Moderna, Obsidian Therapeutics, Skyhawk Therapeutics, Ribometrix, Genomics plc, Merck KGaA, and X-Chem. Established in 1989, Vertex Pharmaceuticals is headquartered in Boston, Massachusetts.

Sector
Healthcare
Industry
Biotechnology
CEO
Reshma Kewalramani
Employees
6,400
Country
US

https://www.vrtx.com

Scorecard

Our own pillar scores, computed from the fundamentals below. They are not Morningstar ratings β€” that data is licensed and we do not redistribute it.

Valuation
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Profitability
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Financial health
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Cash generation
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Key statistics

Market cap
US$130.62B
Enterprise value
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Beta
0.32
Avg volume
1.42M
Revenue per share
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Dividend yield
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52-week range
374.17-560.25
Exchange
NASDAQ

Key ratios

P/E (TTM)
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PEG
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Price / sales
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Price / book
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EV / EBITDA
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Gross margin
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Operating margin
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Net margin
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Current ratio
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Quick ratio
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Debt / equity
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Interest cover
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Income statement

Balance sheet

Cash flow

Trend lines are fitted statistically to past swing highs and lows and projected forward on the assumption the same rhythm continues. It often does not. This is information, not advice.